What Is Tamoxifen?

Izvor: KiWi

Tamoxifen is a medicine in pill form that inhibits star wars apron the game of estrogen. Tamoxifen is used for over 20 years to treat patients with advanced breast cancer. It's used as adjuvant, or extra, therapy following primary treatment for early stage breast cancer. In women at high risk of developing breast cancer, tamoxifen reduces the potential for developing the disease. Tamoxifen continues to be analyzed for the prevention of breast cancer. It's also being examined in the treatment of other kinds of cancer. It's important to note that tamoxifen is also used to treat men with breast cancer.

Tamoxifen Pills

Tamoxifen Citrate Tablets, a nonsterodial anti-estrogen, are for oral administration and contain 15.2 mg of Tamoxifen Citrate (equivalent to 10 mg of tamoxifen). Additionally, each tablet contains as inactive ingredients: carboxymethylcellulose calcium, magnesium stearate, mannitol and starch.

Does Tamoxifen Effect Female Hormones?

Tamoxifen blocks the feminine sex hormone oestrogen. The hormone affects the growth of cells linked to female reproduction, such as those in the breast or the womb. If you have too much oestrogen in-the program, cell development can accelerate to the stage where tumours start to develop. Tamoxifen plays with all the sex hormone for the same proteins - called receptors - located on the surface of cancer cells. It blocks the way for oestrogen - which may otherwise stimulate the cancer cell to divide and make the tumor grow when the drug locks onto the receptors.

Food Restrictions on Tamoxifen

The Food and Drug Administration approved Nolvadex (tamoxifen citrate) for lowering the incidence of breast cancer in women at high-risk for developing the disease, on October 29, 1998. This new indication for tamoxifen, which has been used as a breast cancer therapy for more than 20 years, come from a recent review of the drug, done by the National Cancer Institute (NCI), in women who were judged to be at increased risk of breast cancer. The study showed that tamoxifen reduced the chance of getting breast cancer by 44 percent. The data also showed that its long run effects aren't known, and that tamoxifen treatment didn't entirely eliminate breast cancer risk.